Article
Conservation of fungal and animal nicotinamide adenine dinucleotide phosphate oxidase complexes.
Molecular microbiology - 1 Mar 2015
Scott Barry
Abstract excerpt
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) are a group of eukaryotic flavoenzymes that catalyse the reduction of dioxygen to the superoxide anion using electrons provided by NADPH. An integral membrane flavocytochrome b558 heterodimer, composed of the catalytic subunit gp91(phox) and the adaptor protein p22(phox), is essential for catalytic activity of the mammalian Nox2 complex. Two...
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