Article
Associations Between CYP2B6 rs707265, rs1042389, rs2054675, and Hirschsprung Disease in a Chinese Population.
Digestive diseases and sciences - 1 May 2015
Xu Chao, Chen Pingfa, Xie Hua, Zhu Hairong, Zhu Dongmei, Cai Peng, Huo Weiwei, Qin Yufeng, Li Hongxing, Xia Yankai, Tang Weibing
Abstract excerpt
BACKGROUND: Previous studies suggested that cytochrome P450 participated in the tumor metastasis and migration. CYP2B6 also acts as an important enzyme which metabolize partially or primarily metabolism of drugs, environmental contaminants, and mutagens. The objective of this study was to investigate the influence of CYP2B6 polymorphism on susceptibility of Hirschsprung disease. METHODS: TaqMan assay was...
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