Article
The association of CYP2C9 gene polymorphisms with colorectal carcinoma in Han Chinese.
Clinica chimica acta; international journal of clinical chemistry - 1 May 2007
Liao Ling-Hong, Zhang Hao, Lai Man-Po, Lau Kwok-Wai, Lai Albert Kai-Cheong, Zhang Jin-Hui, Wang Qi, Wei Wei, Chai Jian-Hua, Lung Maria Li, Tai Susan S W, Wu Madeline
Abstract excerpt
BACKGROUND: Cytochrome P450 (CYP) 2C9 is an important enzyme involved in xenobiotics metabolism. This study investigated the association of CYP2C9 gene coding region polymorphisms with colorectal cancer (CRC) in Chinese Han population. METHODS: Four hundred and eighty-three healthy controls and 286 sporadic CRC patients participated in this study. Direct sequencing was used to identify the sequence polymorphisms....
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