Article
Polymorphism of cytochrome P450 2B6 and prostate cancer risk: a significant association in a Japanese population.
International journal of urology : official journal of the Japanese Urological Association - 1 Apr 2009
Kurosaki Takayuki, Suzuki Motofumi, Enomoto Yutaka, Arai Tomio, Sawabe Motoji, Hosoi Takayuki, Homma Yukio, Kitamura Tadaichi
Abstract excerpt
OBJECTIVES: To explore whether Lys262Arg polymorphism of the Cytochrome P450 2B6 (CYP2B6) gene could act as a genetic marker for prostate cancer risk among Japanese men. METHODS: A total of 350 patients with sporadic prostate cancer and 328 controls were examined. A single nucleotide polymorphism with non-synonymous amino acid change located at Lys262Arg of the CYP2B6 gene was genotyped using a TaqMan assay....
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