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Article

Effects of N-glycosylation on hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.

The Biochemical journal - 15 Feb 2015

Li Mo, Tonggu Lige, Tang Lan, Wang Liguo

Abstract excerpt

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are activated by membrane hyperpolarization and conduct an inward cation current, which contributes to rhythmic electrical activity of neural and cardiac pacemaker cells. HCN channels have been shown to undergo N-linked glycosylation, and the N-glycosylation has been shown to be required for membrane trafficking and possibly function. In this...

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Source

Identifiers

PMID: 25423599
DOI: 10.1042/BJ20140692

Genes

HCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Effects of N-glycosylation on hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.PMID 25423599Read ↗

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