Article
The eukaryotic elongation factor eEF1A1 interacts with SAMHD1.
The Biochemical journal - 15 Feb 2015
Morrissey Catherine, Schwefel David, Ennis-Adeniran Valerie, Taylor Ian A, Crow Yanick J, Webb Michelle
Abstract excerpt
Mutations in SAMHD1 cause Aicardi-Goutières syndrome (AGS), a Mendelian inflammatory disease which displays remarkable clinical and biochemical overlap with congenital viral infection. SAMHD1 (SAM domain and HD domain-containing protein 1) has also been defined as an HIV-1 restriction-factor that...
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