Article
No association between rs6897932 in the gene encoding interleukin-7 receptor α and low-grade inflammation or self-reported health - results from the Danish Blood Donor Study.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Feb 2015
Hartling Hans J, Sørensen Cecilie J, Rigas Andreas S, Burgdorf Kristoffer S, Nielsen Susanne D, Pedersen Ole B, Petersen Mikkel S, Sørensen Erik, Kotzé Sebastian, Thørner Lise W, Hjalgrim Henrik, Erikstrup Christian, Ullum Henrik
Abstract excerpt
The T-allele in the single nucleotide polymorphism rs6897932 in the gene encoding the IL-7 receptor α (IL7RA) is associated with reduced risk of autoimmune diseases including multiple sclerosis and also affects the course of HIV infection. Low-grade inflammation (LGI) and self-reported, health-related quality of life (HRQL) are often associated with chronic diseases and widely used in assessing and monitoring...
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