Molecular genetics of Huntington's disease.

Abstract excerpt

Huntington's disease is a neurodegenerative disorder of the brain that is caused by the mutation of the gene which produces a protein called huntingtin (htt). The mutation is based on the continuous repetition of the trinucleotide CAG which in turn makes the protein toxic for the brain cells. As a result neurons which contain the mutant protein begun to atrophy. The loss of those brain cells can cause many...

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