Article
Notch signaling and ageing.
Advances in experimental medicine and biology - 1 Jan 2015
Polychronidou Eleftheria, Vlachakis Dimitrios, Vlamos Panayiotis, Baumann Marc, Kossida Sophia
Abstract excerpt
Notch signaling is a master controller of the neural stem cell and neural development maintaining a significant role in the normal brain function. Notch genes are involved in embryogenesis, nervous system, and cardiovascular and endocrine function. On the other side, there are studies representing the involvement of Notch mutations in sporadic Alzheimer disease, other neurodegenerative diseases such as Down...
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