Article
Physiology and pathology of notch signalling system.
Journal of cellular physiology - 1 May 2006
Bianchi Silvia, Dotti Maria Teresa, Federico Antonio
Abstract excerpt
Notch proteins encode a family of transmembrane receptors that are part of a signalling transduction system known as Notch signalling, an extremely conserved and widely used mechanism regulating programs governing growth, apoptosis and differentiation in metazoans. Notch signalling begins when the Notch receptor binds ligands and ends when the Notch intracellular domain enters the nucleus and activates...
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