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Article

Role of Notch signaling in neurovascular aging and Alzheimer’s disease

28 Dec 2020

Abstract excerpt

The Notch signaling pathway is an evolutionarily conserved cell signaling system known to be involved in vascular development and function. Recent evidence suggests that dysfunctional Notch signaling could play a critical role in the pathophysiology of neurodegenerative diseases. We reviewed current literature on the role of Notch signaling pathway, and specifically Notch receptor genes and proteins, in aging,...

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PMID: 33384205
DOI: 10.1016/j.semcdb.2020.12.011

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