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Article

Construction and Evaluation of Novel Rhesus Monkey Adenovirus Vaccine Vectors

20 Nov 2014

Abstract excerpt

UNLABELLED: Adenovirus vectors are widely used as vaccine candidates for a variety of pathogens, including HIV-1. To date, human and chimpanzee adenoviruses have been explored in detail as vaccine vectors. The phylogeny of human and chimpanzee adenoviruses is overlapping, and preexisting humoral and cellular immunity to both are exhibited in human populations worldwide. More distantly related adenoviruses may...

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PMID: 25410856
DOI: 10.1128/jvi.02950-14

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