Development of chimpanzee adenoviruses as vaccine vectors: challenges and successes emerging from clinical trials

Abstract excerpt

Replication-defective chimpanzee adenovirus vectors are emerging as a promising new class of genetic vaccine carriers. Chimpanzee adenovirus vectors have now reached the clinical stage and appear to be endowed with all the properties needed for human vaccine development, including high quality and magnitude of the immune response induced against the encoded antigens, good safety and ease of manufacturing on a...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Herpesvirus Infections and Treatments
• Share to Immunotherapy and Immune Responses
• Share to Virus-based gene therapy research