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Article

Estrogen receptors genes polymorphisms and age at menarche in idiopathic scoliosis.

BMC musculoskeletal disorders - 19 Nov 2014

Janusz Piotr, Kotwicka Malgorzata, Andrusiewicz Miroslaw, Czaprowski Dariusz, Czubak Jaroslaw, Kotwicki Tomasz

Abstract excerpt

BACKGROUND: The age at menarche (AAM) is commonly in use in patients with IS as one of the maturity indicator suggesting deceleration of the growth velocity. The AAM was suggested to be related to predisposition and curve progression potential of IS. The late age at menarche was reported to be associated with higher prevalence of adolescent idiopathic scoliosis. The age at menarche is determined by both genetic...

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Identifiers

PMID: 25410117
DOI: 10.1186/1471-2474-15-383
PMCID: PMC4247216

Genes

ESR2
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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