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Article

Estrogen Receptor Type 1 and Type 2 Presence in Paravertebral Skeletal Muscles: Expression Level and Relation to Phenotype in Children with Idiopathic Scoliosis.

Genes - 22 Apr 2022

Kotwicki Tomasz, Tomaszewski Marek, Andrusiewicz Mirosław, Śliwa Aleksandra, Rusin Błażej, Kotwicka Małgorzata

Abstract excerpt

The study aimed to detect the presence and assess the expression levels of the estrogen receptors type 1 (ESR1) and type 2 (ESR2) within paravertebral skeletal muscles of female patients with idiopathic scoliosis (IS) in relation to phenotype parameters. Intraoperatively, the muscle samples were obtained from 35 adolescent females. The RT-qPCR, western blot and immunohistochemistry techniques were applied. The...

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Identifiers

PMID: 35627124
DOI: 10.3390/genes13050739
PMCID: PMC9141030

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