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Article

ESR1 as a candidate gene for adolescent idiopathic scoliosis pathogenesis in North-West Indian population.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Aug 2026

Kowra Shipra, Singh Hemender, Singh Vinod, Rai Ekta, Sharma Swarkar

Abstract excerpt

INTRODUCTION: Estrogens are crucial in the development and growth of skeletal systems. Estrogen receptor alpha (ESRα) and beta (ESRβ) are crucial regulators of estrogen response. Estrogen receptor genes (ESR1 and ESR2) have been extensively studied previously for their association with adolescent idiopathic scoliosis (AIS). However, no such study of these genes has been conducted in the North-West Indian...

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Identifiers

PMID: 42289022
DOI: 10.1007/s00586-026-10065-5

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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ESR1 as a candidate gene for adolescent idiopathic scoliosis pathogenesis in North-West Indian population.PMID 42289022Read ↗

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Estrogen Receptor Type 1 and Type 2 Presence in Paravertebral Skeletal Muscles: Expression Level and Relation to Phenotype in Children with Idiopathic Scoliosis.Semantic proximity Read ↗

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