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A relook into the association of the estrogen receptor [alpha] gene (PvuII, XbaI) and adolescent idiopathic scoliosis: a study of 540 Chinese cases.

Spine - 1 Oct 2006

Tang Nelson Leung-Sang, Yeung Hiu-Yan, Lee Kwong-Man, Hung Vivian Wing-Yin, Cheung Catherine Siu-King, Ng Bobby Kin-Wah, Kwok Rachel, Guo Xia, Qin Ling, Cheng Jack Chun-Yiu

Abstract excerpt

STUDY DESIGN: A genetic association study of estrogen receptor-[alpha] gene (ESR1) with adolescent idiopathic scoliosis (AIS) in Chinese. OBJECTIVES: To investigate whether: 1) PvuII and XbaI polymorphisms in ESR1 are predisposition factor for AIS and 2) these polymorphisms correlate with the severity of curvature in AIS. SUMMARY OF BACKGROUND DATA: A common single nucleotide polymorphism (SNP) in ESR1 (XbaI) was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17023856
DOI: 10.1097/01.brs.0000239179.81596.2b

Genes

ESR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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