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Article

Genomic polymorphisms of G-protein estrogen receptor 1 are associated with severity of adolescent idiopathic scoliosis.

International orthopaedics - 1 Mar 2012

Peng Yan, Liang Guoyan, Pei Yuanyuan, Ye Wei, Liang Anjing, Su Peiqiang

Abstract excerpt

PURPOSE: Adolescent idiopathic scoliosis (AIS) is reported to be associated with the two traditional estrogen receptor genes, ESR1 and ESR2. Yet, the novel estrogen receptor G protein-coupled estrogen receptor 1 (GPER) has not been studied. To investigate the association of GPER gene polymorphisms with the onset and deterioration of AIS, we performed a case-control study. METHODS: Clinical information was...

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Source

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Identifiers

PMID: 22002330
DOI: 10.1007/s00264-011-1374-8
PMCID: PMC3291774

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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