Article
Complex two-component signaling regulates the general stress response in Alphaproteobacteria.
Proceedings of the National Academy of Sciences of the United States of America - 2 Dec 2014
Kaczmarczyk Andreas, Hochstrasser Ramon, Vorholt Julia A, Francez-Charlot Anne
Abstract excerpt
The general stress response (GSR) in Alphaproteobacteria was recently shown to be controlled by a partner-switching mechanism that is triggered by phosphorylation of the response regulator PhyR. Activation of PhyR ultimately results in release of the alternative extracytoplasmic function sigma factor σ(EcfG), which redirects transcription toward the GSR. Little is known about the signal transduction pathway(s)...
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