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Article

In vivo selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemether-lumefantrine and dihydroartemisinin-piperaquine in Burkina Faso.

Antimicrobial agents and chemotherapy - 1 Jan 2015

Baraka Vito, Tinto Halidou, Valea Innocent, Fitzhenry Robert, Delgado-Ratto Christopher, Mbonye Martin K, Van Overmeir Chantal, Rosanas-Urgell Anna, Van Geertruyden Jean-Pierre, D'Alessandro Umberto, Erhart Annette

Abstract excerpt

Plasmodium falciparum Pfcrt-76 and Pfmdr1-86 gene polymorphisms were determined during a clinical trial in Burkina Faso comparing the efficacies of dihydroartemisinin-piperaquine (DHA-PPQ) and artemether-lumefantrine (AL). Significant selection of Pfcrt-K76 was observed after exposure to AL and D...

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Identifiers

PMID: 25403659
DOI: 10.1128/AAC.03647-14
PMCID: PMC4291431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25403659-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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