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Article

Selection of pfcrt K76 and pfmdr1 N86 Coding Alleles after Uncomplicated Malaria Treatment by Artemether-Lumefantrine in Mali.

International journal of molecular sciences - 3 Jun 2021

Maiga Hamma, Grivoyannis Anastasia, Sagara Issaka, Traore Karim, Traore Oumar B, Tolo Youssouf, Traore Aliou, Bamadio Amadou, Traore Zoumana I, Sanogo Kassim, Doumbo Ogobara K, Plowe Christopher V, Djimde Abdoulaye A

Abstract excerpt

BACKGROUND: Artemether-lumefantrine is a highly effective artemisinin-based combination therapy that was adopted in Mali as first-line treatment for uncomplicated Plasmodium falciparum malaria. This study was designed to measure the efficacy of artemether-lumefantrine and to assess the selection of the P. falciparum chloroquine resistance transporter (pfcrt) and P. falciparum multi-drug resistance 1 (pfmdr1)...

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Identifiers

PMID: 34205228
DOI: 10.3390/ijms22116057
PMCID: PMC8200001

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Source receipt: pubmed, retrieved 7 Sept 2026.

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