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Article

Identification of genome-wide SNP-SNP and SNP-clinical Boolean interactions in age-related macular degeneration.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015

Riveros Carlos, Vimieiro Renato, Holliday Elizabeth G, Oldmeadow Christopher, Wang Jie Jin, Mitchell Paul, Attia John, Scott Rodney J, Moscato Pablo A

Abstract excerpt

We propose here a methodology to uncover modularities in the network of SNP-SNP interactions most associated with disease. We start by computing all possible Boolean binary SNP interactions across the whole genome. By constructing a weighted graph of the most relevant interactions and via a combi...

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PMID: 25403535
DOI: 10.1007/978-1-4939-2155-3_12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25403535-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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