Article
Role of endometrial cancer abnormal MMR protein in screening Lynch-syndrome families.
International journal of clinical and experimental pathology - 1 Jan 2014
Long Qiongxian, Peng Yong, Tang Zhirong, Wu Cailiang
Abstract excerpt
OBJECTIVE: To identify patients with endometrial cancer with potential Lynch-related DNA mismatch repair (MMR) protein expression defects and to explore the role of these defects in screening for LS. METHODS: Endometrial cancers from 173 patients recruited to the Nanchong Central Hospital were tested for MMR (MLH1, MSH2, PMS2, and MSH6) protein expression using immunohistochemistry (IHC). RESULTS: In the 173...
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