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Article

Molecular patterns in human ulcerative colitis and correlation with response to infliximab.

Inflammatory bowel diseases - 1 Dec 2014

Halloran Brendan, Chang Jessica, Shih David Q, McGovern Dermot, Famulski Konrad, Evaschesen Chad, Fedorak Richard N, Thiesen Aducio, Targan Stephan, Halloran Philip F

Abstract excerpt

BACKGROUND: As a T cell-mediated disease of the colonic epithelium, ulcerative colitis (UC) is likely to share pathogenic elements with other T cell-mediated inflammatory diseases. Recently, microarray analysis revealed large-scale molecular changes in T cell-mediated rejection of kidney and heart transplants. We hypothesized that similar disturbances might be operating in UC and could provide insights into...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25397893
DOI: 10.1097/MIB.0000000000000239
PMCID: PMC4985265

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IFNG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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