Multiomics-empowered Deep Phenotyping of Ulcerative Colitis Identifies Biomarker Signatures Reporting Functional Remission States.

doi:10.1093/ecco-jcc/jjad052

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Multiomics-empowered Deep Phenotyping of Ulcerative Colitis Identifies Biomarker Signatures Reporting Functional Remission States.

Journal of Crohn's & colitis - 20 Oct 2023

Janker Lukas, Schuster Dina, Bortel Patricia, Hagn Gerhard, Meier-Menches Samuel M, Mohr Thomas, Mader Johanna C, Slany Astrid, Bileck Andrea, Brunmair Julia, Madl Christian, Unger Lukas, Hennlich Barbara, Weitmayr Barbara, Del Favero Giorgia, Pils Dietmar, Pukrop Tobias, Pfisterer Nikolaus, Feichtenschlager Thomas, Gerner Christopher

Abstract excerpt

INTRODUCTION: Ulcerative colitis [UC] is a chronic disease with rising incidence and unclear aetiology. Deep molecular phenotyping by multiomics analyses may provide novel insights into disease processes and characteristic features of remission states. METHODS: UC pathomechanisms were assessed by proteome profiling of human tissue specimens, obtained from five distinct colon locations for each of the 12 patients...

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Identifiers

PMID: 36961872
DOI: 10.1093/ecco-jcc/jjad052
PMCID: PMC10588787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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