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Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation

28 Jun 2016

Abstract excerpt

Psychological stress during pregnancy increases the risk of childhood wheeze and asthma. However, the transmitting mechanisms remain largely unknown. Since epigenetic alterations have emerged as a link between perturbations in the prenatal environment and an increased disease risk we used whole genome bisulfite sequencing (WGBS) to analyze changes in DNA methylation in mothers and their children related to...

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PMID: 27349968
DOI: 10.1038/srep28616

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