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Article

Epigenetic Modifications in Placenta are Associated with the Child’s Sensitization to Allergens

17 Apr 2019

Abstract excerpt

Prenatal environmental exposures are considered to contribute to the development of allergic sensitization by epigenetic mechanisms. The role of histone acetylation in the placenta has not been examined yet. We hypothesized that placental histone acetylation at the promoter regions of allergy-related immune regulatory genes is associated with the development of sensitization to allergens in the child. Histones H3...

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PMID: 31111043
DOI: 10.1155/2019/1315257

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