Article
Per3 length polymorphism in patients with type 2 diabetes mellitus.
Hormone molecular biology and clinical investigation - 1 Jun 2014
Karthikeyan Ramanujam, Marimuthu Ganapathy, Sooriyakumar Murugesan, BaHammam Ahmed S, Spence David Warren, Pandi-Perumal Seithikurippu R, Brown Gregory M, Cardinali Daniel P
Abstract excerpt
BACKGROUND: A number of observations support the involvement of circadian clock genes in the regulation of metabolic processes. One of these circadian genes, Per3, exhibits a variable number tandem repeat length polymorphism, consisting of two alleles, namely four and five repeat alleles, in its exon 18. The objective of this study was to examine the existence of Per3 variants in patients with type 2 diabetes...
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