Article
Circadian rhythm genes CLOCK and PER3 polymorphisms and morning gastric motility in humans.
PloS one - 1 Jan 2015
Yamaguchi Mitsue, Kotani Kazuhiko, Tsuzaki Kokoro, Takagi Ayaka, Motokubota Naoko, Komai Naho, Sakane Naoki, Moritani Toshio, Nagai Narumi
Abstract excerpt
BACKGROUND: Clock genes regulate circadian rhythm and are involved in various physiological processes, including digestion. We therefore investigated the association between the CLOCK 3111T/C single nucleotide polymorphism and the Period3 (PER3) variable-number tandem-repeat polymorphism (either 4 or 5 repeats 54 nt in length) with morning gastric motility. METHODS: Lifestyle questionnaires and anthropometric...
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