Article
Polymorphism in the PER3 promoter associates with diurnal preference and delayed sleep phase disorder.
Sleep - 1 May 2010
Archer Simon N, Carpen Jayshan D, Gibson Mark, Lim Gim Hui, Johnston Jonathan D, Skene Debra J, von Schantz Malcolm
Abstract excerpt
STUDY OBJECTIVES: To screen the PER3 promoter for polymorphisms and investigate the phenotypic associations of these polymorphisms with diurnal preference, delayed sleep phase disorder/syndrome (DSPD/DSPS), and their effects on reporter gene expression. DESIGN: Interspecific comparison was used to define the approximate extent of the PER3 promoter as the region between the transcriptional start site and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
