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Article

The role of the fat mass and obesity associated gene (FTO) in breast cancer risk.

BMC medical genetics - 13 Apr 2011

Kaklamani Virginia, Yi Nengjun, Sadim Maureen, Siziopikou Kalliopi, Zhang Kui, Xu Yanfei, Tofilon Sarah, Agarwal Surbhi, Pasche Boris, Mantzoros Christos

Abstract excerpt

BACKGROUND: Obesity has been shown to increase breast cancer risk. FTO is a novel gene which has been identified through genome wide association studies (GWAS) to be related to obesity. Our objective was to evaluate tissue expression of FTO in breast and the role of FTO SNPs in predicting breast cancer risk. METHODS: We performed a case-control study of 354 breast cancer cases and 364 controls. This study was...

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Identifiers

PMID: 21489227
DOI: 10.1186/1471-2350-12-52
PMCID: PMC3089782

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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FTO: the first gene contributing to common forms of human obesity.Semantic proximity Read ↗

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