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Impact of FTO Genetic Variants on Colorectal Cancer Risk: A Case-Control Study.

DNA and cell biology - 1 Mar 2026

Yan Zimo, Zhou Xianlei, Wu Wenlong, Xu Hongxue, Zhang Zhi, Zhang Xuemei

Abstract excerpt

This study aimed to assess the association between fat mass and obesity-associated (FTO) genetic variants and colorectal cancer (CRC) risk in a retrospective case-control cohort. FTO expression in CRC versus normal tissues was analyzed via UALCAN (TCGA), and the regulatory effects of rs9930506 and rs9940128 were assessed using GTEx data. A retrospective analysis was conducted on 870 CRC cases and 870 matched...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41776738
DOI: 10.1177/10445498251413504

Genes

FTO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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