Article
Systems biology approaches for studying the pathogenesis of non-alcoholic fatty liver disease.
World journal of gastroenterology - 7 Nov 2014
Fisher Ciarán P, Kierzek Andrzej M, Plant Nick J, Moore J Bernadette
Abstract excerpt
Non-alcoholic fatty liver disease (NAFLD) is a progressive disease of increasing public health concern. In western populations the disease has an estimated prevalence of 20%-40%, rising to 70%-90% in obese and type II diabetic individuals. Simplistically, NAFLD is the macroscopic accumulation of lipid in the liver, and is viewed as the hepatic manifestation of the metabolic syndrome. However, the molecular...
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