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Article

The Immune Regulator VTCN1 Gene Polymorphisms and Its Impact on Susceptibility to Breast Cancer.

Journal of clinical laboratory analysis - 1 Sept 2015

Tsai Shih-Meng, Wu Szu-Hsien, Hou Ming-Feng, Yang Hlio-Han, Tsai Li-Yu

Abstract excerpt

BACKGROUND: VTCN1, a T-cell regulator, belongs to the immunoglobulin superfamily. It is more highly expressed in tumor tissues than in normal tissues, which suggests that it could serve as a tumor-related agent. We hypothesize the gene variants for this coinhibitory molecule may be associated with the risk of breast cancer, given such gene polymorphisms could affect its related gene expression. METHODS: Genotypes...

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Source

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Identifiers

PMID: 25385143
DOI: 10.1002/jcla.21788
PMCID: PMC6806705

Genes

VTCN1
GCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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