Article
Candidate gene approach evaluates association between innate immunity genes and breast cancer risk in Korean women.
Carcinogenesis - 1 Sept 2009
Lee Ji-Young, Park Ae Kyung, Lee Kyoung-Mu, Park Sue K, Han Sohee, Han Wonshik, Noh Dong-Young, Yoo Keun-Young, Kim Ho, Chanock Stephen J, Rothman Nathaniel, Kang Daehee
Abstract excerpt
OBJECTIVES: This study was conducted to investigate the role of common variation in innate immunity-related genes as susceptibility factors to breast cancer risk in Korean women. METHODS: Total 1536 single-nucleotide polymorphisms (SNPs) in 203 genes were analyzed by Illumina GoldenGate assay in 209 cases and the same numbers of controls. Both SNP and gene-based tests were used to evaluate the association with...
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