Article
Development of a reverse genetics system based on RNA polymerase II for Newcastle disease virus genotype VII.
Virus genes - 1 Feb 2015
Wang Jianzhong, Wang Chunfeng, Feng Na, Wang Hualei, Zheng Xuexing, Yang Songtao, Gao Yuwei, Xia Xianzhu, Yin Renfu, Liu Xiufan, Hu Shunlin, Ding Chan, Yu Shengqing, Cong Yanlong, Ding Zhuang
Abstract excerpt
Newcastle disease virus (NDV) has only a single serotype but diversified genotypes. Genotype VII strains are the prevalent currently circulating genotype worldwide, and in particular, these strains cause outbreaks in waterfowl. In this study, a reverse genetics system for highly virulent NDV isol...
Topics
- Animals
- Artificial Gene Fusion
- Blotting, Western
- Geese
- Genes, Reporter
- Genome, Viral
- Genotype
- Green Fluorescent Proteins
- Microscopy, Fluorescence
- Newcastle disease virus
- Promoter Regions, Genetic
- RNA Polymerase II
- Reverse Genetics