Article
A novel genotype VII Newcastle disease virus vaccine candidate generated by mutation in the L and F genes confers improved protection in chickens.
Veterinary microbiology - 1 Mar 2018
Ji Yanhong, Liu Tao, Du Yingying, Cui Xiaole, Yu Qingzhong, Wang Zhengxiang, Zhang Jinjin, Li Yu, Zhu Qiyun
Abstract excerpt
Administration of vaccines combined with the good management and strict biosecurity is an effective way for Newcastle disease (ND) control. However, vaccine failure is continuously reported in some countries mainly because the antigenic difference between the used vaccine and field strains even they are of one serotype. Therefore, development of antigen-matched ND vaccines is needed to improve the vaccine...
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