Article
Genetic loci associated with circulating levels of very long-chain saturated fatty acids.
Journal of lipid research - 1 Jan 2015
Lemaitre Rozenn N, King Irena B, Kabagambe Edmond K, Wu Jason H Y, McKnight Barbara, Manichaikul Ani, Guan Weihua, Sun Qi, Chasman Daniel I, Foy Millennia, Wang Lu, Zhu Jingwen, Siscovick David S, Tsai Michael Y, Arnett Donna K, Psaty Bruce M, Djousse Luc, Chen Yii-Der I, Tang Weihong, Weng Lu-Chen, Wu Hongyu, Jensen Majken K, Chu Audrey Y, Jacobs David R, Rich Stephen S, Mozaffarian Dariush, Steffen Lyn, Rimm Eric B, Hu Frank B, Ridker Paul M, Fornage Myriam, Friedlander Yechiel
Abstract excerpt
Very long-chain saturated fatty acids (VLSFAs) are saturated fatty acids with 20 or more carbons. In contrast to the more abundant saturated fatty acids, such as palmitic acid, there is growing evidence that circulating VLSFAs may have beneficial biological properties. Whether genetic factors influence circulating levels of VLSFAs is not known. We investigated the association of common genetic variation with...
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