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Article

Effect of rivastigmine or memantine add-on therapy is affected by butyrylcholinesterase genotype in patients with probable Alzheimer's disease.

European neurology - 1 Jan 2015

Han Hyun Jeong, Kwon Jay C, Kim Jung Eun, Kim Shin Gyeom, Park Jong-Moo, Park Kyung Won, Park Key Chung, Park Kee Hyung, Moon So Young, Seo Sang Won, Choi Seong Hye, Cho Soo-Jin

Abstract excerpt

BACKGROUND: The K variant of butyrylcholinesterase (BCHE-K) exhibits a reduced acetylcholine-hydrolyzing capacity; so the clinical response to rivastigmine may differ in Alzheimer's disease (AD) patients with the BCHE-K gene. OBJECTIVE: To investigate the clinical response to rivastigmine transdermal patch monotherapy or memantine plus rivastigmine transdermal patch therapy in AD patients based on the BCHE-K...

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Identifiers

PMID: 25376930
DOI: 10.1159/000366198

Genes

BCHE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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