Article
Mutations in the mitochondrial 12S rRNA gene in elderly Chinese people.
Acta oto-laryngologica - 1 Jan 2015
Zhu Yuhua, Zhao Jiandong, Feng Bo, Su Yu, Kang Dongyang, Yuan Huijun, Zhai Suoqiang, Dai Pu
Abstract excerpt
CONCLUSION: Our data indicate that the mitochondrial 12S rRNA gene, and particularly the A827G mutation, may be associated with susceptibility to age-related hearing loss. OBJECTIVE: Hearing loss associated with aging is common among elderly persons. In all genetic backgrounds, mitochondrial DNA (mtDNA) mutations may be one of the most important factors contributing to aging and age-related hearing loss. The...
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