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Article

Genetic mutations of GJB2 and mitochondrial 12S rRNA in nonsyndromic hearing loss in Jiangsu Province of China.

Journal of translational medicine - 4 Jul 2013

Wei Qinjun, Wang Shuai, Yao Jun, Lu Yajie, Chen Zhibin, Xing Guangqian, Cao Xin

Abstract excerpt

BACKGROUND: Hearing loss is caused by several environmental and genetic factors and the proportion attributed to inherited causes is assumed at 50 ~ 60% . Mutations in GJB2 and mitochondrial DNA (mtDNA) 12S rRNA are the most common molecular etiology for nonsyndromic sensorineural hearing loss (NSHL). The mutation spectra of these genes vary among different ethnic groups. METHODS: To add the molecular etiologic...

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Identifiers

PMID: 23826813
DOI: 10.1186/1479-5876-11-163
PMCID: PMC3706284

Genes

GJB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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