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Article

Molecular analysis of mitochondrial gene mutations in Korean patients with nonsyndromic hearing loss.

International journal of molecular medicine - 1 Aug 2008

Bae Jae Woong, Lee Kyu Yup, Choi Soo Young, Lee Sang Heun, Park Hong-Joon, Kim Un-Kyung

Abstract excerpt

Mutations in mitochondrial DNA (mtDNA) are a major cause of hearing loss. In this study, we performed a systematic mutational screening of the 12S rRNA, tRNA Ser(UCN), tRNA Lys and tRNA Leu(UUR) genes in 227 unrelated patients with nonsyndromic hearing impairment for the first time in a Korean population. We found two individuals with an A1555G mutation, which is a frequency (0.9%) lower than that of other East...

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PMID: 18636170

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UCN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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