Article
Association between ADH1C and ALDH2 polymorphisms and alcoholism in a Turkish sample.
Nordic journal of psychiatry - 1 Apr 2015
Ayhan Yavuz, Gürel Şeref Can, Karaca Özgür, Zoto Teuta, Hayran Mutlu, Babaoğlu Melih, Yaşar Ümit, Bozkurt Atilla, Dilbaz Nesrin, Uluğ Berna Diclenur, Demir Başaran
Abstract excerpt
BACKGROUND: Polymorphisms in the genes encoding alcohol metabolizing enzymes are associated with alcohol dependence. AIM: To evaluate the association between the alcohol dehydrogenase 1C (ADH1C) Ile350Val and aldehyde dehydrogenase 2 (ALDH2) Glu504Lys polymorphisms and alcohol dependence in a Turkish sample. METHODS: 235 individuals (115 alcohol-dependent patients and 120 controls) were genotyped for ADH1C and...
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