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Article

Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma.

European journal of endocrinology - 1 Feb 2015

Sue Mariko, Martucci Victoria, Frey Florina, Lenders Jacques M W, Timmers Henri J, Peczkowska Mariola, Prejbisz Aleksander, Swantje Brede, Bornstein Stefan R, Arlt Wiebke, Fassnacht Martin, Beuschlein Felix, Robledo Mercedes, Pacak Karel, Eisenhofer Graeme

Abstract excerpt

OBJECTIVE: Testing for succinate dehydrogenase subunit B (SDHB) mutations is recommended in all patients with metastatic phaeochromocytomas and paragangliomas (PPGLs), but may not be required when metastatic disease is accompanied by adrenaline production. This retrospective cohort study aimed to establish the prevalence of SDHB mutations among patients with metastatic PPGLs, characterised by production of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25371406
DOI: 10.1530/EJE-14-0756

Genes

SDHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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