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Article

Outcomes of SDHB Pathogenic Variant Carriers.

The Journal of clinical endocrinology and metabolism - 13 Aug 2024

Davidoff Dahlia F, De Abreu Lourenco Richard, Tsang Venessa H M, Benn Diana E, Clifton-Bligh Roderick J

Abstract excerpt

CONTEXT: Carriers of germline pathogenic variants (PVs) in succinate dehydrogenase type B (SDHB) are at increased risk of developing pheochromocytomas and paragangliomas (PPGLs). Understanding their outcomes can guide recommendations for risk assessment and early detection. OBJECTIVE: We performed a systematic review and meta-analysis of the following outcomes in SDHB PV carriers: age-specific risk of developing...

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Topics

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Share to Adrenal Gland Neoplasms
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

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Source

Open in PubMed Open full text

Identifiers

PMID: 38605204
DOI: 10.1210/clinem/dgae233
PMCID: PMC11318991

Genes

SDHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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