Article
Clinical manifestations of familial paraganglioma and phaeochromocytomas in succinate dehydrogenase B (SDH-B) gene mutation carriers.
Clinical endocrinology - 1 Oct 2008
Srirangalingam Umasuthan, Walker Lisa, Khoo Bernard, MacDonald Fiona, Gardner Daphne, Wilkin Terence J, Skelly Robert H, George Emad, Spooner David, Monson John P, Grossman Ashley B, Akker Scott A, Pollard Patrick J, Plowman Nick, Avril Norbert, Berney Daniel M, Burrin Jacky M, Reznek Rodney H, Kumar V K Ajith, Maher Eamonn R, Chew Shern L
Abstract excerpt
OBJECTIVE: Phaeochromocytomas and paragangliomas are familial in up to 25% of cases and can result from succinate dehydrogenase (SDH) gene mutations. The aim of this study was to describe the clinical manifestations of subjects with SDH-B gene mutations. DESIGN: Retrospective case-series. PATIENTS: Thirty-two subjects with SDH-B gene mutations followed up between 1975 and 2007. Mean follow-up of 5.8 years (SD...
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