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Article

Durable and deep response to CVD chemotherapy in SDHB-mutated metastatic paraganglioma: case report.

Frontiers in endocrinology - 1 Jan 2024

Zhang Chenyan, Wei Yuanfeng, Cheng Ke, Cao Dan

Abstract excerpt

Introduction: Succinate dehydrogenase subunit B (SDHB)-mutated paragangliomas (PGLs) are rare neuroendocrine tumors characterized by increased malignancy, readily metastasizing, and poorer prognosis. Here we report a case of SDHB-mutated metastatic PGL, wherein the patient showed significant tumor shrinkage and complete symptom remission following chemotherapy. We aim to contribute additional evidence to the...

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Identifiers

PMID: 39744181
DOI: 10.3389/fendo.2024.1483516
PMCID: PMC11688215

Genes

SDHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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