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Article

Biochemically silent abdominal paragangliomas in patients with mutations in the succinate dehydrogenase subunit B gene.

The Journal of clinical endocrinology and metabolism - 1 Dec 2008

Timmers Henri J L M, Pacak Karel, Huynh Thanh T, Abu-Asab Mones, Tsokos Maria, Merino Maria J, Baysal Bora E, Adams Karen T, Eisenhofer Graeme

Abstract excerpt

CONTEXT: Patients with adrenal and extra-adrenal abdominal paraganglioma (PGL) almost invariably have increased plasma and urine concentrations of metanephrines, the O-methylated metabolites of catecholamines. We report four cases of biochemically silent abdominal PGL, in which metanephrines were normal despite extensive disease. OBJECTIVE: Our objective was to identify the mechanism underlying the lack of...

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Share to Abdominal Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Microscopy, Electron

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Share to Tomography, X-Ray Computed

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Source

Open in PubMed Open full text

Identifiers

PMID: 18840642
DOI: 10.1210/jc.2008-1093
PMCID: PMC2626451

Genes

SDHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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