Article
An interaction between a FNDC5 variant and obesity modulates glucose metabolism in a Chinese Han population.
PloS one - 1 Jan 2014
Tang Shanshan, Zhang Rong, Jiang Feng, Wang Jie, Chen Miao, Peng Danfeng, Yan Jing, Bao Yuqian, Hu Cheng, Jia Weiping
Abstract excerpt
BACKGROUND: To investigate the impact of common variants of FNDC5 on type 2 diabetes and clinical traits related to glucose metabolism in a large Chinese population sample. METHODS: Three tagging single nucleotide polymorphisms within the region of the FNDC5 gene were selected and genotyped in 6822 participants. Detailed clinical investigations and biochemistry measurements were carried out in all of the...
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