Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations between rs3480 and rs16835198 gene polymorphisms of FNDC5 with type 2 diabetes mellitus susceptibility: a meta-analysis.

Frontiers in endocrinology - 1 Jan 2022

Yang Xianqin, Ni Li, Sun Junyu, Yuan Xiaolu, Li Dezhong

Abstract excerpt

Background: FNDC5 is a novel and important player in energy regulation related to glucose metabolism and insulin levels. Thus, it may affect the incidence of type 2 diabetes mellitus (T2DM). Nevertheless, the association between FNDC5 single nucleotide polymorphisms (SNPs) and susceptibility to T2DM remains unclear. The aim of this meta-analysis was to explore whether the SNPs, rs3480 and rs16835198, are...

Topics

Join the communities discussing this publication.

Alleles
Diabetes Mellitus, Type 2
Fibronectins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 36004352
DOI: 10.3389/fendo.2022.946982
PMCID: PMC9393395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations between rs3480 and rs16835198 gene polymorphisms of FNDC5 with type 2 diabetes mellitus susceptibility: a meta-analysis.PMID 36004352Read ↗

FTO gene variants (rs9939609, rs8050136 and rs17817449) and type 2 diabetes mellitus risk: A Meta-Analysis.Semantic proximity Read ↗

Association of CDKAL1 RS10946398 Gene Polymorphism with Susceptibility to Diabetes Mellitus Type 2: A Meta-Analysis.Semantic proximity Read ↗

An interaction between a FNDC5 variant and obesity modulates glucose metabolism in a Chinese Han population.Semantic proximity Read ↗

Genetic Variants of TPCN2 Associated with Type 2 Diabetes Risk in the Chinese Population.Semantic proximity Read ↗

Association of uncoupling protein-2 -866G/A and Ala55Val polymorphisms with susceptibility to type 2 diabetes mellitus: A meta-analysis of case-control studies.Semantic proximity Read ↗

RS3480 Polymorphism of FNDC5/Irisin Is Associated with Type 2 Diabetes Mellitus in Maya-Mestizo Women.Semantic proximity Read ↗

Association between FABP2 Ala54Thr polymorphisms and type 2 diabetes mellitus risk: a HuGE Review and Meta-Analysis.Semantic proximity Read ↗

NADPH oxidase 5 is a novel gene for type 2 diabetes susceptibility determined by gene-body mass index and gene-environment interactionsSemantic proximity Read ↗

In vitro and in silico analysis of three variants associated with type 2 diabetes.Semantic proximity Read ↗

Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population.Semantic proximity Read ↗

Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.Semantic proximity Read ↗

Variations with modest effects have an important role in the genetic background of type 2 diabetes and diabetes-related traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.